Neoadjuvant therapy
Scenario 1:
Complete Response, No Surgery Needed
Complete Response, No Surgery Needed
Scenario 2:
Initial Response, Later Recurrence
Initial Response, Later Recurrence
Scenario 3:
No Complete Response, Surgery Needed
No Complete Response, Surgery Needed
40-50%Complete Response
40-50%Complete Response
No Surgery Needed
+- 30%Recurrence
Metastatic Spread
50-60%Partial Response
Surgery Needed
Surgery Needed
Surgery - LAR
Surgery - APR
Surgery - LAR
Surgery - APR
Regular Follow-Ups
No Surgery Needed Initially