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July 15, 2025

What’s Really Holding Your Clinical Trial Back?

Rethinking Participant Experience in Clinical Trials

Illustration of a worried researcher talking to three patients outside a ‘CLINICAL TRIAL’ door.

Clinical research has come a long way—innovative therapies, advanced protocols, and global collaborations. Yet, many studies still stall not due to scientific flaws but because of everyday challenges faced by participants. Missed visits, confusing instructions, and waning motivation can ripple into delayed timelines and incomplete data. The true challenge lies in the participant experience.

Every interaction a participant has—from the moment they hear about a study to their final follow-up—shapes their willingness to stay engaged. Clear information reduces anxiety. Timely reminders prevent no-shows. Easy access to support builds trust. When these elements work together, trials run more smoothly, allowing research teams to focus on advancing science rather than troubleshooting.

What Does a Participant-Centered Platform Look Like in Practice?

A participant-centered approach in clinical trials is grounded in key principles: clarity of information, timely support, ease of access, and participant autonomy. Digital tools like electronic Clinical Outcome Assessments (eCOAs)—including electronic Patient-Reported Outcomes (ePROs)—are increasingly used to put these principles into action, helping reduce participant burden and improve engagement and data quality.

Among them, the Patient Education and Engagement Portal (PEEP) stands out for integrating these elements into a seamless experience. Precare’s platform is designed to enhance clinical trial processes by focusing on tailored solutions in key areas like patient recruitment, engagement, consent, and long-term study follow-ups. By leveraging data-driven strategies and digital outreach, including social media, Precare identifies and engages potential participants effectively. The platform also simplifies the informed consent process and allows for seamless data collection with user-friendly digital solutions compliant with regulations. Here’s how PEEP works:

  • Participants receive personalized educational content through short, tailored videos that explain procedures, visits, and expectations in a way that’s easy to absorb—right from a tablet or phone. Instead of one-size-fits-all instructions, each step is contextualized and accessible.
  • A built-in interactive communication channel allows real-time messaging with study staff. No more waiting days for answers—participants can ask questions directly within the platform, increasing clarity and reducing dropouts.
  • The comprehensive FAQ section offers instant, searchable access to protocol details, visit prep, and common concerns. It replaces scattered PDFs with a centralized, always-available knowledge base.
  • All digital resources — from prep checklists to support contacts—are organized in one secure hub. Participants aren’t left wondering where to look for critical information.
  • An integrated calendar helps manage appointments with automated reminders by email, SMS, or push notification. This helps participants stay on track while significantly reducing missed visits.
  • Through customizable questionnaires, participants can complete ePROs quickly and intuitively, helping research teams collect cleaner, more consistent data with less effort.
  • The streamlined consent process walks users through each section step by step, with built-in explanations and digital signature capture. It ensures comprehension and speeds up onboarding—no paper, no scanning.
  • Finally, simplified tracking tools allow participants to monitor their own progress in the study while providing researchers with up-to-date insights into adherence and engagement.

Combining these features in a single, user-friendly platform, PEEP shifts the trial experience from fragmented and reactive into coordinated and participant-friendly—making it easier for participants to stay informed and engaged. Toward Smoother, More Reliable Studies

Early adopters of patient-centered platforms consistently report fewer missed visits, higher retention rates, and richer data quality. When participants feel acknowledged, informed, and supported, they're more likely to remain active and compliant throughout the study.

As digital engagement tools evolve, the future of clinical trials will be defined not only by scientific rigor but by a focus on the human experience. Platforms like PEEP exemplify how user-focused design transforms clinical trials into collaborative journeys toward improved health outcomes.


References

  1. Jiang X, Timmons M, Boroda E, Onakomaiya M. Impact of platform design and usability on adherence and retention: randomized web- and mobile-based longitudinal study. J Particip Med 2025;17:e50225.
  2. Precare. Solutions [Internet]. Canada: Precare; 2025 [cited 2025 Jul 15]. Available from: https://precare.ca/solutions/
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